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IVABRADINE (eye VAB ra deen) treats heart failure. It works by decreasing your heart rate, which decreases the amount of work your heart has to do.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with a glass of water. Take it as directed on the prescription label at the same time every day. Take it with food. Avoid grapefruit juice. Keep taking it unless your care team tells you to stop.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 6 months for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Adagrasib
-Ceritinib
-Certain antibiotics, such as chloramphenicol, clarithromycin, telithromycin
-Certain antivirals for HIV or hepatitis
-Certain medications for fungal infections, such as ketoconazole, itraconazole, posaconazole, voriconazole
-Idelalisib
-Lonafarnib
-Nefazodone
-Ribociclib
-Tucatinib
This medication may also interact with the following:
-Certain medications for blood pressure, heart disease, irregular heartbeat
-Certain medications for seizures, such as phenobarbital or phenytoin
-Rifampin
-St. John's wort
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
You may see bright spots or lines while you are taking this medication. This can happen when the light around you changes, such as going from dark to bright. It is most common during the first 2 months of treatment and may go away as you continue taking this medication. Use caution while driving or operating machinery, especially while driving at night.
Talk to your care team if you may be pregnant. Serious fetal side effects can occur if you take this medication during pregnancy. Contraception is recommended while taking this medication. Your care team can help you find the option that works for you.
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If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
-Increase in blood pressure
-Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
-Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Luminous phenomena—seeing temporary bright or flashing spots, halos around lights, shifting patterns or colors
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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