Nutritional Supplement

Zinc

Zinc is an essential mineral that is a component of more than 300 enzymes needed to repair wounds, maintain fertility in adults and growth in children, synthesize protein, help cells reproduce, preserve vision, boost immunity, and protect against free radicals, among other functions.

References

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41. Liszewski RF. The effect of zinc on wound healing: a collective review. J Am Osteopath Assoc 1981;81:104-6 [review].

42. Pories WJ, Henzel JH, Rob CG, Strain WH. Acceleration of healing with zinc sulfate. Ann Surg 1967;165:432-6.

43. Lansdown ABG. Zinc in the healing wound. Lancet 1996;347:706-7 [editorial].

44. Ågren MS. Studies on zinc in wound healing. Acta Derm Venereol Suppl 1990;154:1-36 [review].

45. Ågren MS. Zinc in wound repair. Arch Dermatol 1999;135:1273-4 [letter].

46. Sandstead HH. Understanding zinc: Recent observations and interpretations. J Lab Clin Med 1994;124:322-7.

47. Tenaud I, Sainte-Marie I, Jumbou O, et al. In vitro modulation of keratinocyte wound healing integrins by zinc, copper and manganese. Br J Dermatol 1999;140:26-34.

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56. Simkin PA. Oral zinc sulphate in rheumatoid arthritis. Lancet 1976;ii:539-42.

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58. Job C, Menkes CJ, de Gery A, et al. Zinc sulphate in the treatment of rheumatoid arthritis. Arthrit Rheum 1980;23:1408.

59. Simkin PA. Treatment of rheumatoid arthritis with oral zinc sulfate. Agents Actions 1981;8(suppl):587-96.

60. Pfeiffer CJ, Cho CH, Cheema A, Saltman D. Reserpine-induced gastric ulcers: protection by lysosomal stabilization due to zinc. Eur J Pharmacol 1980;61:347-53.

61. Jimenez E, Bosch F, Galmes JL, Banos JE. Meta-analysis of efficacy of zinc acexamate in peptic ulcer. Digestion 1992;51:18-26.

62. Frommer DJ. The healing of gastric ulcers by zinc sulphate. Med J Aust 1975;22(21):793-6.

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64. Crofton RW, Glover SC, Ewen SWB, et al. Zinc absorption in celiac disease and dermatitis herpetiformis: a test of small intestinal function. Am J Clin Nutr 1983;38:706-12.

65. Solomons NW, Rosenberg IH, Sandstead HH. Zinc nutrition in celiac sprue. Am J Clin Nutr 1976;29:371-5.

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67. Nishiwaki H, Kato S, Sugamoto S, et al. Ulcerogenic and healing impairing actions of monochloramine in rat stomachs: effects of zinc L-carnosine, polaprezinc. J Physiol Pharmacol 1999;50:183-95.

68. Arakawa T, Satoh H, Nakamura A, et al. Effects of zinc L-carnosine on gastric mucosal and cell damage caused by ethanol in rats. Correlation with endogenous prostaglandin E2. Dig Dis Sci 1990;35:559-66.

69. Cho CH, Ogle CW. A correlative study of the antiulcer effects of zinc sulphate in stressed rats. Eur J Pharmacol 1978;48:97-105.

70. Frommer DJ. The healing of gastric ulcers by zinc sulphate. Med J Aust 1975;22(21):793-6.

71. Kashimura H, Suzuki K, Hassan M, et al. Polaprezinc, a mucosal protective agent, in combination with lansoprazole, amoxicillin, and clarithromycin increases the cure rate of Helicobacter pylori infection. Aliment Pharmacol Ther 1999;13(4):483-7.

72. Imes S, Plinchbeck BR, Dinwoodie A, et al. Iron, folate, vitamin B-12, zinc, and copper status in out-patients with Crohn's disease: effect of diet counseling. J Am Dietet Assoc 1987;87:928-30.

73. Sandstead HH. Zinc deficiency in Crohn's disease. Nutr Rev 1982;40:109-12.

74. Driscoll RH Jr, Meredith SC, Sitrin M, et al. Vitamin D deficiency and bone disease in patients with Crohn's disease. Gastroenterology 1982;83:1252-8.

75. Frommer DJ. The healing of gastric ulcers by zinc sulphate. Med J Aust 1975;22(21):793-6.

76. Eby GA, Halcomb WW. Use of topical zinc to prevent recurrent herpes simplex infection: review of literature and suggested protocols. Med Hypotheses 1985;17:157-65.

77. Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. Br J Dermatol 1981;104:191-4.

78. Apisariyakulm A, Buddhasukh D, Apisariyakul S, Ternai B. Zinc monoglycerolate is effective against oral herpetic sores. Med J Aust 1990;152:54.

79. Pang JF. Relation between treatment with traditional Chinese medicine for recurrent aphthous ulcer and human zinc and copper. Zhongguo Zhong Xi Yi Jie He Za Zhi 1992;12:280-2, 260-1 [in Chinese].

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81. Merchant HW, Gangarosa LP, Glassman AB, Sobel RE. Zinc sulfate supplementation for treatment of recurring oral ulcers. South Med J 1977;70:559-61.

82. Wray D. A double-blind trial of systemic zinc sulfate in recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol 1982;53:469-72.

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85. Harper DS, Mueller LJ, Fine JB, et al. Clinical efficacy of a dentifrice and oral rinse containing sanguinaria extract and zinc chloride during 6 months of use. J Periodontol 1990;61(6):352-8.

86. Mauriello SM, Bader JD. Six-month effects of a sanguinarine dentifrice on plaque and gingivitis. J Periodontol 1988;59(4):238-43.

87. Eby GA, Halcomb WW. Use of topical zinc to prevent recurrent herpes simplex infection: review of literature and suggested protocols. Med Hypotheses 1985;17:157-65.

88. Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. Br J Dermatol 1981;104:191-4.

89. Apisariyakulm A, Buddhasukh D, Apisariyakul S, Ternai B. Zinc monoglycerolate is effective against oral herpetic sores. Med J Aust 1990;152:54.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.

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