Urinary Incontinence

Health Condition

Urinary Incontinence

  • Magnesium

    In a double blind study, women with urge incontinence reported improvement after supplementing with magnesium.

    Dose:

    150 mg twice daily

    Magnesium
    ×
    In a double blind study, women with urge incontinence took approximately 150 mg of magnesum twice daily for one month, and reported improvement, including fewer episodes of urge incontinence, less frequent urination, and fewer awakenings at night to urinate.2 This confirmed an earlier double-blind study showing that a similar amount of magnesium reduced symptoms of urge incontinence.3

  • Vinpocetine

    In a small, preliminary study, some men and women with urge incontinence reported reduced symptoms and also improved in laboratory measures of bladder muscle control when supplementing with vinpocetine.

    Dose:

    5 mg three times daily for two weeks, then 10 mg three times daily for two weeks
    Vinpocetine
    ×
    Vinpocetine is a semisynthetic derivative of vincamine, one of the major active compounds found in periwinkle. In a small, preliminary study, men and women with urge incontinence were given 5 mg of vinpocetine three times daily for two weeks, then 10 mg three times daily for an additional two weeks. About half of the subjects reported reduced symptoms of urge incontinence and also improved in laboratory measures of bladder muscle control.4 However, a small, double-blind trial found improvement in only one of several measures of urge incontinence.5 More double blind trials are needed to confirm these findings.

  • Vitamin B12

    Vitamin B12 deficency can cause urinary incontinence that may be corrected with supplementation.

    Dose:

    See a doctor to test for deficiency
    Vitamin B12
    ×
    Vitamin B12 deficency can cause urinary incontinence that can be cured with B12 supplementation.6 One preliminary study,7 but not others,8,9 have found that low blood levels of B12 were associated with urinary incontinence in older people. Controlled trials are needed to determine whether B12 supplementation might be useful as a treatment for the common types of urinary incontinence.

  • Vitamin D

    Higher blood levels of vitamin D are associated with lower risk of urinary incontinence in women.

    Dose:

    Refer to label instructions
    Vitamin D
    ×
    Vitamin D may be important for normal muscle function, including muscles that help control urinary continence.10,11 Higher blood levels of vitamin D are associated with lower risk of urinary incontinence in women, according to one preliminary study.12 Controlled trials are needed to determine whether vitamin D supplements can help prevent or treat urinary incontinence.
What Are Star Ratings
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

References

1. Santiagu SK, Arianayagam M, Wang A, Rashid P. Urinary incontinence-pathophysiology and management outline. Aust Fam Physician 2008;37:106-10.

2. Boschert S. Milk of magnesia may help ease urinary urge incontinence. Fam Pract News 2003;33:46.

3. Gordon D, Groutz A, Ascher-Landsberg J, et al. Double-blind, placebo-controlled study of magnesium hydroxide for treatment of sensory urgency and detrusor instability: preliminary results. Br J Obstet Gynaecol 1998;105:667-9.

4. Truss MC, Stief CG, Uckert S, et al. Initial clinical experience with the selective phosphodiesterase-I isoenzyme inhibitor vinpocetine in the treatment of urge incontinence and low compliance bladder. World J Urol 2000;18:439-43.

5. Truss MC, Stief CG, Uckert S, et al. Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside. World J Urol 2001;19:344-50 [review].

6. Healton EB, Savage DG, Brust JC, et al. Neurologic aspects of cobalamin deficiency. Medicine (Baltimore) 1991;70:229-45.

7. Rana S, D'Amico F, Merenstein JH. Relationship of vitamin B12 deficiency with incontinence in older people. J Am Geriatr Soc 1998;46:931-2.

8. Garcia A, Smith M, Freedman M. Vitamin B12 deficiency and incontinence in older people. Can J Urol 2000;7:1077-80.

9. Endo JO, Chen S, Potter JF, et al. Vitamin B(12) deficiency and incontinence: is there an association? J Gerontol A Biol Sci Med Sci 2002;57:M583-7.

10. Crescioli C, Morelli A, Adorini L, et al. Human bladder as a novel target for vitamin D receptor ligands. J Clin Endocrinol Metab 2005;90:962-72.

11. Schröder A, Colli E, Maggi M, Andersson KE. Effects of vitamin D(3) analogue in a rat model of bladder outlet obstruction. BJU Int 2006;98:637-42.

12. 3] Badalian SS, Rosenbaum PF. Vitamin D and pelvic floor disorders in women: results from the National Health and Nutrition Examination Survey. Obstet Gynecol 2010;115:795-803.

13. Dallosso HM, Matthews RJ, McGrother CW, et al. The association of diet and other lifestyle factors with the onset of overactive bladder: a longitudinal study in men. Public Health Nutr 2004;7:885-91.

14. Dallosso HM, McGrother CW, Matthews RJ, et al. The association of diet and other lifestyle factors with overactive bladder and stress incontinence: a longitudinal study in women. BJU Int 2003;92:69-77.

15. Dallosso H, Matthews R, McGrother C, Donaldson M. Diet as a risk factor for the development of stress urinary incontinence: a longitudinal study in women. Eur J Clin Nutr 2004;58:920-6.

16. Higa R, Lopes MH, dos Reis MJ. Risk factors for urinary incontinence in women. Rev Esc Enferm USP 2008;42:187-92 [review, in Portuguese].

17. Kincade JE, Dougherty MC, Carlson JR, et al. Factors related to urinary incontinence in community-dwelling women. Urol Nurs 2007;27:307-17.

18. Bryant CM, Dowell CJ, Fairbrother G. Caffeine reduction education to improve urinary symptoms. Br J Nurs 2002;11:560-5.

19. Swithinbank L, Hashim H, Abrams P. The effect of fluid intake on urinary symptoms in women. J Urol 2005;174:187-9.

20. Tomlinson BU, Dougherty MC, Pendergast JF, et al. Dietary caffeine, fluid intake and urinary incontinence in older rural women. Int Urogynecol J Pelvic Floor Dysfunct 1999;10:22-8.

21. Dowd TT, Campbell JM, Jones JA. Fluid intake and urinary incontinence in older community-dwelling women. J Community Health Nurs 1996;13:179-86.

22. Bump RC, McClish DK. Cigarette smoking and urinary incontinence in women. Am J Obstet Gynecol 1992;167:1213-8.

23. Koskimaki J, Hakama M, Huhtala H, Tammela TL. Association of smoking with lower urinary tract symptoms. J Urol 1998;159:1580-2.

24. Shamliyan T, Wyman J, Bliss DZ, et al. Prevention of urinary and fecal incontinence in adults. Evid Rep Technol Assess (Full Rep) 2007;161:1-379 [review].

25. Jiang K, Novi JM, Darnell S, Arya LA. Exercise and urinary incontinence in women. Obstet Gynecol Surv 2004;59:717-21 [review].

26. Townsend MK, Danforth KN, Rosner B, et al. Physical activity and incident urinary incontinence in middle-aged women. J Urol 2008;179:1012-6.

27. Danforth KN, Shah AD, Townsend MK, et al. Physical activity and urinary incontinence among healthy, older women. Obstet Gynecol 2007;109:721-7.

28. Wolin KY, Luly J, Sutcliffe S, et al. Risk of urinary incontinence following prostatectomy: the role of physical activity and obesity. J Urol 2010;183:629-33.

29. Hunskaar S. A systematic review of overweight and obesity as risk factors and targets for clinical intervention for urinary incontinence in women. Neurourol Urodyn 2008;27:749-57 [review].

30. Subak LL, Richter HE, Hunskaar S. Obesity and urinary incontinence: epidemiology and clinical research update. J Urol 2009;182(6 Suppl):S2-7 [review].

31. Subak LL, Wing R, West DS, et al. Weight loss to treat urinary incontinence in overweight and obese women. N Engl J Med 2009;360:481-90.

32. Brown JS, Wing R, Barrett-Connor E, et al. Lifestyle intervention is associated with lower prevalence of urinary incontinence: the Diabetes Prevention Program. Diabetes Care 2006;29:385-90.

Copyright © 2024 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.

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