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Health Condition

Retinopathy

About This Condition

The term retinopathy indicates damage to the retina at the back of the eye. Several conditions, such as type 1 and type 2 diabetes, and high blood pressure, can lead to the development of retinopathy.

Symptoms

Retinopathy often has no early warning signs. If retinopathy progresses, partial or total blindness may result.

Other Therapies

In treating advanced retinopathy, doctors may use laser surgery to shrink abnormal blood vessels at the back of the eye. This treatment results in a loss of some peripheral (side) vision, a sacrifice that preserves the remaining field of vision. Laser surgery for retinopathy may also reduce color and night vision. A surgical alternative to laser surgery, called vitrectomy, is sometimes used if the eye has become cloudy due to hemorrhage (bleeding). Vitrectomy replaces the vitreous humor (transparent fluid in the interior of the eyeball behind the lens) with a salt solution.

References

1. Scharrer A, Ober M. Anthocyanosides in the treatment of retinopathies. Klin Monatsblatt Augenheilk 1981;178:386-9.

2. Perossini M, Guidi G, Chiellini S, Siravo D. Diabetic and hypertensive retinopathy therapy with Vaccinium myrtillus anthocyanosides (Tegens®): Double-blind, placebo-controlled clinical trial. Ann Ottalmol Clin Ocul 1987;113:1173-7 [in Italian].

3. Fromantin M. Procyanidolic oligomers in the treatment of fragile capillaries and diabetic retinopathy. Med Int 1981;16:432-4 [in French].

4. Verin MM, Vildy A, Maurin JF. Retinopathies and OPC. Bordeaux Medicale 1978;11:1467-74 [in French].

5. Arne JL. Contribution to the study of procyanidolic oligomeres: Endotelon in diabetic retinopathy (in regard to 30 observations). Gaz Med de France 1982;89:3610–4 [in French].

6. Varma SD. Inhibition of aldose reductase by flavonoids: Possible attenuation of diabetic complications. Progr Clin Biol Res 1986;213:343-58.

7. Glacet-Bernard A, Coscas G, Chabanel A, et al. A randomized, double-masked study on the treatment of retinal vein occlusion with troxerutin. Am J Ophthalmol 1994;118:421-9.

8. Lanthony P, Cosson JP. The course of color vision in early diabetic retinopathy treated with Ginkgo biloba extract. A preliminary double-blind versus placebo study. J Fr Ophtalmol 1988;11:671-4 [in French].

9. Jialal I, Joubert SM. The biochemical profile in Indian patients with non-insulin-dependent diabetes in the young with retinopathy. Diabetes Metabol 1985;11:262-5.

10. McNair P, Christiansen C, Madsbad S, et al. Hypomagnesemia, a risk factor in diabetic retinopathy. Diabetes 1978;27:1075-8.

11. Erasmus RT, Olukoga AO, Alanamu RA, et al. Plasma magnesium and retinopathy in black African diabetics. Trop Geogr Med 1989;41:234-7.

12. Brooser G, Anda L, Doman J. Preliminary report on the use of ethyl apovincaminate in affections of the eyeground. Arzneimittelforschung 1976;26:1973-5.

13. Kornerup T, Strom L. Vitamin B12 and retinopathy in juvenile diabetics. Acta Paediatr 1958:47:646-51.

14. Alieva ZA, Gadzhiev RV, Sultanov M. Possible role of the antioxidant system of the vitreous body in delaying the development of diabetic retinopathy. Oftalmol Zh 1985;(3):142-5 [in Russian].

15. Johnson L, Quinn GE, Abbasi S, et al. Effect of sustained pharmacological vitamin E levels on incidence and severity of retinopathy of prematurity: A controlled clinical trial. J Pediatr 1989;114:827-38.

16. Raju TN, Langenberg P, Bhutani V, Quinn GE. Vitamin E prophylaxis to reduce retinopathy of prematurity: a reappraisal of published trials. J Pediatr 1997;131:844-50.

17. Hittner HM, Godio LB, Rudoph AJ, et al. Retrolental fibroplasia: efficacy of vitamin E in a double-blind clinical study of preterm infants. N Engl J Med 1981;305:1365-71.

18. Runge P, Muller DP, McAllister J, et al. Oral vitamin E supplements can prevent the retinopathy of abetalipoproteinaemia. Br J Ophthalmol 1986;70:166-73.

19. De Hoff JB, Ozazewski J. Alpha tocopherol to treat diabetic retinopathy. Am J Ophthalmol 1954;37:581-2.

20. Bursell S-E, Schlossman DK, Clermont AC, et al. High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes. Diabetes Care 1999;22:1245-51.

21. Crary EJ, McCarty MF. Potential clinical applications for high-dose nutritional antioxidants. Med Hypotheses 1984;13:77-98.

22. Anonymous. Retinopathic effect of sucrose-rich diets due to fructose. Nutr Rev 1982;40:117-8,128.

23. Gaby AR. Fructose, glycosylation, and aging. Townsend Letter for Doctors and Patients 1999;Apr:107-8.

24. Paetkau ME, Boyd TAS, Winship B, Grace M. Cigarette smoking and diabetic retinopathy. Diabetes 1977;26:46-9.

25. McCance DR, Hadden DR, Atkinson AB, et al. Long-term glycaemic control and diabetic retinopathy. Lancet 1989;2:824-8.

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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2018.

Drugs used to treat RETINOPATHY. Select drug name to view medication information and pricing