Multiple Sclerosis

Health Condition

Multiple Sclerosis

The right diet is the key to managing many diseases and to improving general quality of life. For this condition, scientific research has found benefit in the following healthy eating tips.

  • Swank Diet

    Supplementing with 5 grams of cod liver oil daily, eating foods high in linoleic acid from natural vegetable oils, such as sunflower oil and sunflower seeds, while eating a diet low in animal fats and hydrogenated oils may reduce disability and lengthen life.
    Swank Diet
    ×

    The amount and type of fat eaten may affect both the likelihood of healthy people getting the disease and the outcome of the disease for those already diagnosed with MS. For many years, the leading researcher linking dietary fat to MS risk and progression has been Dr. Roy Swank.

    In one of Dr. Swank’s reports, a low-fat diet was recommended to 150 people with MS.35 Although hydrogenated oils, peanut butter, and animal fat (including fat from dairy) were dramatically reduced or eliminated, 5 grams per day of cod liver oil were added, and linoleic acid from vegetable oil was used. After 34 years, the mortality rate among people consuming an average of 17 grams of saturated fat per day was only 31%, compared with 79% among those who consumed a higher average of 25 grams of saturated fat per day. People who began to follow the low-fat diet early in the disease did better than those who changed their eating habits after the disease had progressed.

    A survey of people in 36 different countries also suggests that the types of fat people eat may impact MS.36 In that report, people with MS who ate foods high in polyunsaturated and monounsaturated fatty acids were likely to live longer than those who ate more saturated fats. In another survey, researchers gathered information from nearly 400 people (half with MS) over three years.37 They found that people who ate more fish were less likely to develop MS, while those who ate pork, hot dogs, and other foods high in animal (saturated) fats were at greater risk. This same report found consumption of vegetable protein, fruit juice, and foods rich in vitamin C, thiamine, riboflavin, calcium, and potassium correlated with a decreased MS risk. Eating sweets was linked to an increased risk.

    Despite research showing improvement with a low-fat diet in some people with MS, the link between foods containing animal fat and MS risk may not necessarily be due to the fat itself. Preliminary evidence from one report revealed an association between eating dairy foods (cows’milk, butter, and cream) and an increased prevalence of MS, yet no link was found between (high fat) cheese and MS in that same report.38

    MS has been associated with a variety of dietary components apparently unrelated to fat intake,39 and the link between MS and diet remains poorly understood. Nonetheless, the most consistent links to date appear to involve certain foods containing animal fat. People with MS wishing to pursue a nutritional approach that incorporates an understanding of this research should consult with a doctor familiar with the “Swank diet.”

  • Gluten-Free

    Some people with MS avoid gluten in hopes of diminishing symptoms because a study reported a link between grains and MS development, however, further research is needed to determine effectiveness.
    Gluten-Free
    ×

    Some people with MS avoid gluten (a protein found in wheat, rye, and barley) in hopes of diminishing symptoms, because a preliminary study reported that consumption of grain (bread and pasta) was linked to development of MS.40 However, another trial found an association between eating cereals and breads and reduced MS risk.41 Other researchers have found gluten sensitivity to be no more common among people with MS than among healthy people.42 Thus, the idea that avoiding gluten will help MS remains speculative.

References

1. Landtblom AM, Flodine U, Karlsson M, et al. Multiple sclerosis and exposure to solvents, ionizing radiation and animals. Scand J Work Environ Health 1993;19:399-404.

2. Haahr S, Koch-Henriksen N, Moller-Larsen A, et al. Increased risk of multiple sclerosis after late Epstein-Barr virus infection: a historical prospective study. Mult Scler 1995;1:73-7.

3. Sedel F, Papeix C, Bellanger A, et al. High doses of biotin in chronic progressive multiple sclerosis: A pilot study. Mult Scler Relat Disord 2015;4:159–69.

4. Tourbah A, Lebrun-Frenay C, Edan G, et al. MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study. Mult Scler 2016 Sep 1 [Epub ahead of print].

5. Cendrowski W. Multiple sclerosis and MaxEPA. Br J Clin Pract 1986;40:365-7.

6. Weinstock-Guttman B, Baier M, Park Y, et al. Low fat dietary intervention with omega-3 fatty acid supplementation in multiple sclerosis patients. Prostaglandins Leukot Essent Fatty Acids 2005;73:397-404.

7. Torkildsen O, Wergeland S, Bakke S, et al. Omega-3 fatty acid treatment in multiple sclerosis (OFAMS Study): a randomized, double-blind, placebo-controlled trial. Arch Neurol 2012;69:1044-51.

8. Goldberg P, Fleming MC, Picard EH. Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. Med Hypothesis 1986;21:193-200.

9. DeLuca HF, Zierold C. Mechanisms and functions of vitamin D. Nutr Rev 1998;56(2 Pt 2):S4-10 [review].

10. Yasui M, Yase Y, Ando K, et al. Magnesium concentration in brains from multiple sclerosis patients. Acta Neurol Scand 1990;81:197-200.

11. Yasui M, Ota K. Experimental and clinical studies on dysregulation of magnesium metabolism and the aetiopathogenesis of multiple sclerosis. Magnes Res 1992;5:295-302.

12. Korwin-Piotrowska T, Nocoñ D, Stankowska-Chomicz A, et al. Experience of Padma 28 in multiple sclerosis. Phytother Res 1992;6:133-6.

13. Goldberg P, Fleming MC, Picard EH. Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. Med Hypothesis 1986;21:193-200.

14. DeLuca HF, Zierold C. Mechanisms and functions of vitamin D. Nutr Rev 1998;56(2 Pt 2):S4-10 [review].

15. Yasui M, Yase Y, Ando K, et al. Magnesium concentration in brains from multiple sclerosis patients. Acta Neurol Scand 1990;81:197-200.

16. Yasui M, Ota K. Experimental and clinical studies on dysregulation of magnesium metabolism and the aetiopathogenesis of multiple sclerosis. Magnes Res 1992;5:295-302.

17. Rosnowska M, Cendrowski W, Piesio B, Wieczorkiewicz M.Effect of short-term administration of sunflower oil on the blood serum level of linoleic and arachidonic acids and lipids in multiple sclerosis, Neurol Neurochir Pol, 1980;14:27-37 [in Polish].

18. Werbach M. Nutritional Influences on Illness. Tarzana, CA: Third Line Press, 1996, 434 [review].

19. Dworkin RH, Bates D, Millar JH, Paty DW. Linoleic acid and multiple sclerosis: a reanalysis of three double-blind trials. Neurology 1984;34:1441-5 [review].

20. Brochet B, Orgogozo JM, Guinot P, et al. Pilot study of Ginkgolide B, a PAF-acether specific inhibitor in the treatment of acute outbreaks of multiple sclerosis. Rev Neurol (Paris) 1992;148:299-301 [in French].

21. Koprowski H, Spitsin SV, Hooper DC. Prospects for the treatment of multiple sclerosis by raising serum levels of uric acid, a scavenger of peroxynitrite. Ann Neurol 2001;49:139.

22. Goldberg P, Fleming MC, Picard EH. Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. Med Hypothesis 1986;21:193-200.

23. DeLuca HF, Zierold C. Mechanisms and functions of vitamin D. Nutr Rev 1998;56(2 Pt 2):S4-10 [review].

24. Yasui M, Yase Y, Ando K, et al. Magnesium concentration in brains from multiple sclerosis patients. Acta Neurol Scand 1990;81:197-200.

25. Yasui M, Ota K. Experimental and clinical studies on dysregulation of magnesium metabolism and the aetiopathogenesis of multiple sclerosis. Magnes Res 1992;5:295-302.

26. Dines KC, Powell HC. Mast cell interactions with the nervous system: relationship to mechanisms of disease. J Neuropathol Exp Neurol 1997;56:627-40.

27. Stern EI. The intraspinal injection of vitamin B1 for the relief of intractable pain, and for inflammatory and degenerative diseases of the central nervous system. Am J Surg 1938;34:495.

28. Moore MT. Treatment of multiple sclerosis with nicotinic acid and vitamin B1. Arch Int Med 1940;65:18.

29. Dines KC, Powell HC. Mast cell interactions with the nervous system: relationship to mechanisms of disease. J Neuropathol Exp Neurol 1997;56:627-40.

30. Stern EI. The intraspinal injection of vitamin B1 for the relief of intractable pain, and for inflammatory and degenerative diseases of the central nervous system. Am J Surg 1938;34:495.

31. Moore MT. Treatment of multiple sclerosis with nicotinic acid and vitamin B1. Arch Int Med 1940;65:18.

32. Munger KL, Levin LI, Hollis BW, et al. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA 2006;296:2832-8.

33. Burton JM, Kimball S, Vieth R, et al. A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis. Neurology 2010;74:1852-9.

34. Stein MS, Liu Y, Gray OM, et al. A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis. Neurology 2011;77:1611-8.

35. Swank RL. Multiple sclerosis: fat-oil relationship. Nutrition 1991;7:368-76.

36. Esparza ML, Saski S, Kesteloot H. Nutrition, latitude, and multiple sclerosis mortality: an ecologic study. Am J Epidemiol 1995;142:733-7.

37. Ghadirian P, Jain M, Ducic S, et al. Nutritional factors in the aetiology of multiple sclerosis: a case-control study in Montreal, Canada. Int J Epidemiol 1998;27:845-52.

38. Malosse D, Perron H, Sasco A, Seigneurin JM. Correlation between milk and dairy product consumption and multiple sclerosis prevalence: a worldwide study. Neuroepidemiology 1992;11:304-12.

39. Tola MR, Granieri E, Malagu S, et al. Dietary habits and multiple sclerosis. A retrospective study in Ferrara, Italy. Acta Neurol (Napoli) 1994;16:189-97.

40. Esparza ML, Saski S, Kesteloot H. Nutrition, latitude, and multiple sclerosis mortality: an ecologic study. Am J Epidemiol 1995;142:733-7.

41. Ghadirian P, Jain M, Ducic S, et al. Nutritional factors in the aetiology of multiple sclerosis: a case-control study in Montreal, Canada. Int J Epidemiol 1998;27:845-52.

42. Hadjivassiliou M, Gibson A, Davies-Jones GA, et al. Does cryptic gluten sensitivity play a part in neurological illness? Lancet 1996;347:369-71.

43. Mortensen JT, Bronnum-Hansen H, Rasmussen K. Multiple sclerosis and organic solvents. Epidemiology 1998;9:168-71.

44. Juntunen J, Kinnunen E, Antti-Poika M, Koskenvuo M. Multiple sclerosis and occupational exposure to chemicals: a co-twin control study of a nationwide series of twins. Br J Ind Med 1989;46:417-9.

45. Landtblom AM, Flodin U, Soderfeldt B, et al. Organic solvents and multiple sclerosis: a synthesis of the current evidence. Epidemiology 1996;7:429-33 [review].

46. Blisard KS, Kornfeld M, McFeeley PJ, Smialek JE. The investigation of alleged insecticide toxicity: a case involving chlordane exposure, multiple sclerosis, and peripheral neuropathy. J Forensic Sci 1986;31:1499-504.

47. Landtblom AM, Flodine U, Karlsson M, et al. Multiple sclerosis and exposure to solvents, ionizing radiation and animals. Scand J Work Environ Health 1993;19:399-404.

48. Krebs JM, Park RM, Boal WL. A neurological disease cluster at a manufacturing plant. Arch Environ Health 1995;50:190-5.

49. Emre M, de Decker C. Effects of cigarette smoking on motor functions in patients with multiple sclerosis. Arch Neurol 1992;49:1243-7.

50. Fung YK, Meade AG, Rack EP, Blotcky AJ. Brain mercury in neurodegenerative disorders. J Toxicol Clin Toxicol 1997;35:49-54.

51. Siblerud RL, Kienholz E. Evidence that mercury from silver dental fillings may be an etiological factor in multiple sclerosis. Sci Total Environ 1994;142:191-205.

52. Bangsi D, Ghadirian P, Ducic S, et al. Dental amalgam and multiple sclerosis: a case-control study in Montreal, Canada. Int J Epidemiol 1998;27:667-71.

53. Craelius W. Comparative epidemiology of multiple sclerosis and dental caries. J Epidemiol Community Health 1978;32:155-65.

Copyright © 2024 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.

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