Gastritis

Health Condition

Gastritis

About This Condition

Gastritis is a broad term for inflammation of the stomach lining, also called the gastric mucosa.

This condition can be caused by many factors and, in some cases, may lead to an ulcer. For that reason, many of the same nutrients, herbs, and lifestyle changes for a peptic ulcer might also help someone with gastritis.

Bacterial infection, most notably with Helicobacter pylori, is a major cause of gastritis. H. pylori is the same bacterium responsible for most cases of peptic ulcer. When considering treatments for gastritis, many researchers now look for substances that eradicate H. pylori, including bismuth and antibiotics.

Other causes of gastritis include intake of caustic poisons, alcohol, and some medications (such as aspirin or adrenal corticosteroids), as well as physical stress from the flu, major surgery, severe burns, or injuries. For some people, a drug allergy or food poisoning can cause gastritis. Atrophic gastritis is a form of gastritis found particularly in the elderly, where stomach cells are destroyed, potentially leading to pernicious anemia.

Symptoms

Acute gastritis is typically characterized by nonspecific abdominal pain. Since gastritis often occurs in severely ill, hospitalized people, its symptoms may be eclipsed by other, more severe symptoms. Gastritis that is caused by H. pylori eventually leads to peptic ulcers, which are characterized by a dull ache in the upper abdomen that usually occurs two to three hours after a meal; the ache is typically relieved by eating.

Other Therapies

Acute gastritis caused by trauma, stress, or severe illness usually heals rapidly when the underlying cause is resolved. Nonsteroidal anti-inflammatory drugs (NSAIDs) and ethanol are common stomach tissue irritants and their use should be limited in people with gastritis.

References

1. Akyön Y. Effect of antioxidants on the immune response of Helicobacter pylori. Clin Microbiol Infect 2002;8:438-41.

2. Wang X, Willén R, Wadström T. Astaxanthin-rich algal meal and vitamin C inhibit Helicobacter pylori infection in BALB/cA mice. Antimicrob Agents Chemother 2000;44:2452-7.

3. Bennedsen M, Wang X, Willén R, et al. Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunol Lett 1999;70:185-9.

4. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: a prospective, randomized, double blind, and placebo controlled study. Phytomedicine 2008;15:391-9.

5. Maruyama K, Kashiwazaki K, Toyama K, Tsuchiya M. Usefulness of Hi-Z fine granule (gamma-Oryzanol) for the treatment of autonomic instability in gastrointestinal system. Shinyaku To Rinsho 1976;25:124 [in Japanese].

6. Takemoto T, Miyoshi H, Nagashima H. Clinical trial of Hi-Z fine granules (gamma-oryzanol) on gastrointestinal symptoms at 375 hospitals (Japan). Shinyaku To Rinsho 1977;26 [in Japanese].

7. Salim AS. Sulfhydryl-containing agents in the treatment of gastric bleeding induced by non-steroidal anti-inflammatory drugs. Can J Surg 1993;36(1):53-8.

8. Farinati F, Cardin R, Della Libera G, et al. Effects of N-acetyl-L-cysteine in patients with chronic atrophic gastritis and nonulcer dyspepsia: a phase III pilot study. Curr Ther Res 1997;58:724-33.

9. Houdijk AP, Van Leeuwen PA, Boermeester MA, et al. Glutamine-enriched enteral diet increases splanchnic blood flow in the rat. Am J Physiol 1994;267(6 Pt 1):G1035-40.

10. Wilmore DW, Smith RJ, O'Dwyer ST, et al. The gut: a central organ after surgical stress. Surgery 1988;104:917-23.

11. Yan R, Sun Y, Sun R. Early enteral feeding and supplement of glutamine prevent occurrence of stress ulcer following severe thermal injury. Chung Hua Cheng Hsing Shao Shang Wai Ko Tsa Chih 1995;11(3):189-92.

12. Brzozowski T, Konturek SJ, Sliwowski Z, et al. Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing. J Gastroenterol 1997;32(4):442-52.

13. Drake IM, Mapstone NP, Schorah CJ, et al. Reactive oxygen species activity and lipid peroxidation in Helicobacter pylori associated gastritis: relation to gastric mucosal ascorbic acid concentrations and effect of H pylori eradication. Gut 1998;42(6):768-71.

14. Waring AJ, Drake IM, Schorah CJ, et al. Ascorbic acid and total vitamin C concentrations in plasma, gastric juice, and gastrointestinal mucosa: effects of gastritis and oral supplementation. Gut 1996;38(2):171-6.

15. Jarosz M, Dzieniszewski J, Dabrowska-Ufniarz E, et al. Effects of high dose vitamin C treatment on Helicobacter pylori infection and total vitamin C concentration in gastric juice. Eur J Cancer Prev 1998;7:449-54.

16. Salim AS. Sulfhydryl-containing agents in the treatment of gastric bleeding induced by non-steroidal anti-inflammatory drugs. Can J Surg 1993;36(1):53-8.

17. Farinati F, Cardin R, Della Libera G, et al. Effects of N-acetyl-L-cysteine in patients with chronic atrophic gastritis and nonulcer dyspepsia: a phase III pilot study. Curr Ther Res 1997;58:724-33.

18. Houdijk AP, Van Leeuwen PA, Boermeester MA, et al. Glutamine-enriched enteral diet increases splanchnic blood flow in the rat. Am J Physiol 1994;267(6 Pt 1):G1035-40.

19. Wilmore DW, Smith RJ, O'Dwyer ST, et al. The gut: a central organ after surgical stress. Surgery 1988;104:917-23.

20. Yan R, Sun Y, Sun R. Early enteral feeding and supplement of glutamine prevent occurrence of stress ulcer following severe thermal injury. Chung Hua Cheng Hsing Shao Shang Wai Ko Tsa Chih 1995;11(3):189-92.

21. Brzozowski T, Konturek SJ, Sliwowski Z, et al. Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing. J Gastroenterol 1997;32(4):442-52.

22. Spirichev VB, Levachev MM, Rymarenko TV, et al. The effect of administration of beta-carotene in an oil solution on its blood serum level and antioxidant status of patients with duodenal ulcer and erosive gastritis. Vopr Med Khim 1992;38(6):44-7 [in Russian].

23. Palli D, Decarli A, Cipriani F, et al. Plasma pepsinogens, nutrients, and diet in areas of Italy at varying gastric cancer risk. Cancer Epidemiol Biomarkers Prev 1991;1(1):45-50.

24. Zhang ZW, Patchett SE, Perrett D, et al. Gastric mucosal and luminal beta-carotene concentrations in patients with chronic H pylori infection. Gut 1996;38(suppl 1):A5 [abstract W11].

25. Spirichev VB, Levachev MM, Rymarenko TV, et al. The effect of administration of beta-carotene in an oil solution on its blood serum level and antioxidant status of patients with duodenal ulcer and erosive gastritis. Vopr Med Khim 1992;38:44-7 [in Russian].

26. Tsubono Y, Okubo S, Hayashi M, et al. A randomized controlled trial for chemoprevention of gastric cancer in high-risk Japanese population; study design, feasibility and protocol modification. Jpn J Cancer Res 1997;88:344-9.

27. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 167.

28. Beil W, Birkholz C, Sewing KF. Effects of flavonoids on parietal cell acid secretion, gastric mucosal prostaglandin production and Helicobacter pylori growth. Arzneimittelforschung 1995;45:697-700.

29. Rekka EA, Kourounakis AP, Kourounakis PN. Investigation of the effect of chamazulene on lipid peroxidation and free radical processes. Res Commun Mol Pathol Pharmacol 1996;92(3):361-4.

30. Salim AS. Sulfhydryl-containing agents in the treatment of gastric bleeding induced by non-steroidal anti-inflammatory drugs. Can J Surg 1993;36(1):53-8.

31. Farinati F, Cardin R, Della Libera G, et al. Effects of N-acetyl-L-cysteine in patients with chronic atrophic gastritis and nonulcer dyspepsia: a phase III pilot study. Curr Ther Res 1997;58:724-33.

32. Houdijk AP, Van Leeuwen PA, Boermeester MA, et al. Glutamine-enriched enteral diet increases splanchnic blood flow in the rat. Am J Physiol 1994;267(6 Pt 1):G1035-40.

33. Wilmore DW, Smith RJ, O'Dwyer ST, et al. The gut: a central organ after surgical stress. Surgery 1988;104:917-23.

34. Yan R, Sun Y, Sun R. Early enteral feeding and supplement of glutamine prevent occurrence of stress ulcer following severe thermal injury. Chung Hua Cheng Hsing Shao Shang Wai Ko Tsa Chih 1995;11(3):189-92.

35. Brzozowski T, Konturek SJ, Sliwowski Z, et al. Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing. J Gastroenterol 1997;32(4):442-52.

36. Bae EA, Han MJ, Kim NJ, Kim DH. Anti-Helicobacter pylori activity of herbal medicines. Biol Pharm Bull 1998;21(9):990-2.

37. Beil W, Birkholz C, Sewing KF. Effects of flavonoids on parietal cell acid secretion, gastric mucosal prostaglandin production and Helicobacter pylori growth. Arzneimittelforschung 1995;45:697-700.

38. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 167.

39. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 167.

40. Frommer DJ. The healing of gastric ulcers by zinc sulphate. Med J Aust 1975;22(21):793-6.

41. Frommer DJ. The healing of gastric ulcers by zinc sulphate. Med J Aust 1975;22(21):793-6.

42. Aiuti F, Paganelli R. Food allergy and gastrointestinal diseases. Ann Allergy 1983;51(two Pt 2):275-80 [review].

43. Reimann H-J, Lewin J. Gastric mucosal reactions in patients with food allergy. Am J Gastroenterol 1988;83:1212-9.

44. Tsugane S, Tei Y, Takahashi T, et al. Salty food intake and risk of Helicobacter pylori infection. Jpn J Cancer Res 1994;85(5):474-8.

45. Jooseens JV, Geboers J. Nutrition and gastric cancer. Nutr Cancer 1981;2:250-61.

46. Yeoh KG, Kang JY, Yap I, et al. Chili protects against aspirin-induced gastroduodenal mucosal injury in humans. Dig Dis Sci 1995;40(3):580-3.

47. Chou T. Wake up and smell the coffee. Caffeine, coffee, and the medical consequences. West J Med 1992;157(5):544-53 [review].

48. Elta GH, Behler EM, Colturi TJ. Comparison of coffee intake and coffee-induced symptoms in patients with duodenal ulcer, nonulcer dyspepsia, and normal controls. Am J Gastroenterol 1990;85(10):1339-42.

49. Altman C, Ladouch A, Briantais MJ, et al. Antral gastritis in chronic alcoholism. Role of cirrhosis and Helicobacter pylori. Presse Med 1995;24(15):708-10 [in French].

50. Robbins SL, Cotran RS, Kumar V. Pathologic Basis of Disease 3rd ed. Philadelphia, PA: WB Saunders Co, 1984, 809-14.

51. Brenner H, Berg G, Lappus N, et al. Alcohol consumption and Helicobacter pylori infection: results from the German National Health and Nutrition Survey. Epidemiology 1999;10:214-8.

52. Scheiman JM. NSAIDs, gastrointestinal injury, and cytoprotection. Gastroenterology Clinics of North America 1996;25(2):279-98 [review].

Copyright © 2024 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.

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