Diarrhea

Health Condition

Diarrhea

About This Condition

Diarrhea is any attack of frequent, watery stools.

Diarrhea can be triggered by many different conditions. Acute diarrhea is often caused by an infection and may require medical management. The primary role of nutrition in acute diarrhea is to prevent depletion of fluid, sodium, potassium, and calories. Replenishment of all four has been achieved with “rehydration solutions” and with a variety of foods, from salted carrot soup to peeled scraped apple to rice gruel. However, diarrhea severe enough to necessitate the use of rehydration solutions requires direct medical supervision. Therefore, nutritional approaches to overcoming depletion of fluid, sodium, potassium, and calories are not discussed here, but rather should be discussed with a doctor. Diarrhea-induced low blood sugar, dehydration, or electrolyte imbalance can be serious or even life-threatening, particularly if prolonged in children.

A healthcare provider should be consulted if diarrhea continues for more than a few days, as it may indicate a more serious health condition. Diarrhea alternating with constipation may be a sign of irritable bowel syndrome (IBS).

Symptoms

Normal bowel habits vary considerably from person to person depending on age, diet, cultural factors, and individual physiology. However, loose watery stools occurring three or more times in one day is generally considered abnormal. In some instances, diarrhea may be accompanied by cramping abdominal pain, nausea, vomiting, fever, loss of appetite, and bloody or foul-smelling stools.

Other Therapies

Rest, along with fluid replacement using Pedialyte®, Ceralyte®, or Infalyte®, is often recommended. Severe diarrhea, especially in children and the elderly, may require hospitalization for urgent fluid and electrolyte replacement in order to correct dehydration.

References

1. Werbach MR. Nutritional influences on Illness, 2d ed. Tarzana, CA: Third Line Press, 1993, 256-61 [review].

2. Bhan MK, Bhandari N. The role of zinc and vitamin A in persistent diarrhea among infants and young children. J Pediatr Gastroenterol Nutr 1998;26:446-53 [review].

3. Crane JK, Hoque KM. Zinc for infectious diarrhea in developed countries: should we be sprinkling our own lawns? J Pediatr Gastroenterol Nutr 2008;46:484-5.

4. Sarker SA, Casswall TH, Mahalanabis D, et al. Successful treatment of rotavirus diarrhea in children with immunoglobulin from immunized bovine colostrum. Pediatr Infect Dis J 1998;17:1149-54.

5. Mitra AK, Mahalanabis D, Ashraf H, et al. Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: a double- blind, controlled clinical trial. Acta Paediatr 1995;84:996-1001.

6. Okhuysen PC, Chappell CL, Crabb J, et al. Prophylactic effect of bovine anti-Cryptosporidium hyperimmune colostrum immunoglobulin in healthy volunteers challenged with Cryptosporidium parvum. Clin Infect Dis 1998;26:1324-9.

7. Greenberg PD, Cello JP. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1996;13:348-54.

8. Casswall TH, Sarker SA, Albert MJ, et al. Treatment of Helicobacter pylori infection in infants in rural Bangladesh with oral immunoglobulins from hyperimmune bovine colostrum. Aliment Pharmacol Ther 1998;12:563-8.

9. Huppertz HI, Rutkowski S, Busch DH, et al. Bovine colostrum ameliorates diarrhea in infection with diarrheagenic Escherichia coli, shiga toxin-producing E. Coli, and E. coli expressing intimin and hemolysin. J Pediatr Gastroenterol Nutr 1999;29:452-6.

10. Warny M, Fatimi A, Bostwick EF, et al. Bovine immunoglobulin concentrate-clostridium difficile retains C difficile toxin neutralising activity after passage through the human stomach and small intestine. Gut 1999;44:212-7.

11. Brines RD, Brock JH. The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human apolactoferrin to proteolytic digestion. Biochim Biophys Acta 1983;759:229-35.

12. Loeb H, Vandenplas Y, Wursch P, Guesry P. Tannin-rich pod for treatment of acute-onset diarrhea. J Pediatr Gastroenterol Nutr 1989;8:480-5.

13. Eherer AH, Porter J, Fordtran JS. Effect of psyllium, calcium polycarbophil, and wheat bran on secretory diarrhea induced by phenolphthalein. Gastroenterol 1993;104:1007-12.

14. Quartarone G. Role of PHGG as a dietary fiber: a review article. Minerva Gastroenterol Dietol 2013 Dec;59:329-40.

15. Danczak E. Glucosamine and plant lectins in autistic spectrum disorders: an initial report on 6 children with uncontrolled diarrhoea. J Nutr Environ Med2004;14:327-330.

16. Yalcin SS, Yurdakok K, Tezcan I, Oner L. Effect of glutamine supplementation on diarrhea, interleukin-8 and secretory immunoglobulin A in children with acute diarrhea. J Pediatr Gastroenterol Nutr 2004;38:494-501.

17. Eherer AH, Porter J, Fordtran JS. Effect of psyllium, calcium polycarbophil, and wheat bran on secretory diarrhea induced by phenolphthalein. Gastroenterol 1993;104:1007-12.

18. Koch J, Tuveson J, Carlson T, Schmidt J. SB-300: a new and effective therapy for HIV-associated diarrhea. Poster presented at the Seventh European Conference on Clinical Aspects and Treatment of HIV-Infection, Lisbon, Portugal, October 23-27, 1999.

19. DuPont HL, Tidmarsh G. An open label pilot study to investigate the safety and effectiveness of orally administered Provir (SP-303) capsules in the symptomatic treatment of acute nonspecific diarrhea and traveler's diarrhea. South San Francisco, CA: Shaman Pharmaceuticals, 1998, unpublished.

20. Dicesare D, DuPont HL, Mathewson JJ, et al. A double-blind, randomized, placebo-controlled study of SP-303 in the symptomatic treatment of acute diarrhea among travelers to Mexico and Jamaica. Abstract presented at the Infectious Diseases Society of America, 36th Annual Meeting, Denver, CO, November 10, 1998.

21. Ettedgui G, Schael IP, Porter S, Pennington J. A double-blind, randomized, placebo-controlled, multi-dose, phase II study to assess the safety and efficacy of SP-303 in the symptomatic treatment of acute diarrhea among adult residents of Venezuela: oral administration of 125 mg, 250 mg, or 500 mg of SP-303 given every 6 hours for 48 hours. South San Francisco, CA: Shaman Pharmaceuticals, 1998, unpublished.

22. Holodniy M, Koch J, Mistal M, et al. A double blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS. Am J Gastroenterol 1999;94:3267-73.

23. Koch J. A phase III, double-blind, randomized, placebo-controlled multi-center study of SP-303 (Provir™) in the symptomatic treatment of diarrhea in patients with acquired immunodeficiency syndrome (AIDS). Posters presented at the 13th international AIDS Conference in Durba, South Africa, July 14, 2000.

24. Khin-Maung-U, Myo-Khin, Nyunt-Nyunt-Wai, et al. Clinical trial of berberine in acute watery diarrhoea. Br Med J 1985;291:1601-5.

25. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York: Pharmaceutical Products Press, 1994, 51-4.

26. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and Beaconsfield, UK: Beaconsfield Publishers Ltd, 1988, 101-2.

27. Duke JA. CRC Handbook of Medicinal Plants. Boca Raton, FL: CRC Press, 1985, 209.

28. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York: Pharmaceutical Products Press, 1994, 51-4.

29. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and Beaconsfield, UK: Beaconsfield Publishers Ltd, 1988, 101-2.

30. Duke JA. CRC Handbook of Medicinal Plants. Boca Raton, FL: CRC Press, 1985, 209.

31. Eherer AH, Porter J, Fordtran JS. Effect of psyllium, calcium polycarbophil, and wheat bran on secretory diarrhea induced by phenolphthalein. Gastroenterol 1993;104:1007-12.

32. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York: Pharmaceutical Products Press, 1994, 51-4.

33. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and Beaconsfield, UK: Beaconsfield Publishers Ltd, 1988, 101-2.

34. Duke JA. CRC Handbook of Medicinal Plants. Boca Raton, FL: CRC Press, 1985, 209.

35. Achterrath-Tuckerman U, Kunde R, et al. Pharmacological investigations with compounds of chamomile. V. Investigations on the spasmolytic effect of compounds of chamomile and Kamillosan® on isolated guinea pig ileum. Planta Med 1980;39:38-50.

36. Duke JA. CRC Handbook of Medicinal Plants. Boca Raton, FL: CRC Press, 1985, 209.

37. Haffejee IE. Effect of oral folate on duration of acute infantile diarrhoea. Lancet 1988;2:334-5 [letter].

38. Ashraf H, Rahman MM, Fuchs GJ, Mahalanabis D. Folic acid in the treatment of acute watery diarrhoea in children: a double-blind, randomized, controlled trial. Acta Pædiatr 1998;87:1113-5.

39. Khin-Maung-U, Myo-Khin, Nyunt-Nyunt-Wai, et al. Clinical trial of berberine in acute watery diarrhoea. Br Med J 1985;291:1601-5.

40. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 166-7.

41. Konig M, Scholz E, Hartmann R, et al. Ellagitannins and complex tannins from Quercus petraea bark. J Nat Prod 1994;57:1411-5.

42. Schilcher H. Phytotherapy in Paediatrics. Stuttgart, Germany: Medpharm Scientific Publishers, 1997, 49-50.

43. Khin-Maung-U, Myo-Khin, Nyunt-Nyunt-Wai, et al. Clinical trial of berberine in acute watery diarrhoea. Br Med J 1985;291:1601-5.

44. Weiss RF. Meuss AR, trans. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum and Beaconsfield: Beaconsfield Publishers Ltd, 1985:180-2.

45. Hoffmann D. The New Holistic Herbal, 3rd ed. Shaftesbury, Dorset, UK: Element, 1990:223.

46. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York: Pharmaceutical Products Press, 1994, 51-4.

47. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and Beaconsfield, UK: Beaconsfield Publishers Ltd, 1988, 101-2.

48. Duke JA. CRC Handbook of Medicinal Plants. Boca Raton, FL: CRC Press, 1985, 209.

49. Fawzi WW, Mbise R, Spiegelman D, et al. Vitamin A supplements and diarrheal and respiratory tract infections among children in Dar es Salaam, Tanzania. J Pediatr 2000;137:660-7.

50. Su Z. Acupuncture treatment of infantile diarrhea: a report of 1050 cases. J Tradit Chin Med 1992;12:120-1.

51. Feng WL. Acupuncture treatment for 30 cases of infantile chronic diarrhea. J Tradit Chin Med 1989;9:106-7.

52. Lin YC. Observation of therapeutic effects of acupuncture treatment in 170 cases of infantile diarrhea. J Tradit Chin Med 1987;7:203-4.

53. Cao Y. Personal experience on acupuncture treatment of diarrhea. J Tradit Chin Med 1990;10:163-7.

54. Cao Y. Personal experience on acupuncture treatment of diarrhea. J Tradit Chin Med 1990;10:251-6.

55. Lin Y, Zhou Z, Shen W, et al. Clinical and experimental studies on shallow needling technique for treating childhood diarrhea. J Tradit Chin Med 1993;13:107-14.

56. James JM, Burks AW. Food-associated gastrointestinal disease. Curr Opin Pediatr 1996;8:471-5 [review].

57. Bowie MD, Hill ID, Mann MD. Response of severe infantile diarrhoea to soya-based feeds. S Afr Med J 1988;73:343-5.

58. Babb RR. Coffee, sugars and chronic diarrhea. Postgrad Med 1984;75:82, 86-7.

59. Hyams JS, Etienne NL, Leichtner AM, Theuer RC. Carbohydrate malabsorption following fruit juice ingestion in young children. Pediatr 1988;82:64-8.

60. Barness LA. Safety considerations with high ascorbic acid dosage. Ann NY Acad Sci 1975;258:523-8 [review].

Copyright © 2024 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.

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