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Drug

Taliglucerase Alfa

Pronounced

"TAL-i-GLOO-ser-ase AL-fa"

Uses

Taliglucerase is used to treat a certain rare genetic problem (Gaucher disease). Taliglucerase replaces a certain natural substance (an enzyme called glucocerebrosidase) that is missing in people with Gaucher disease.

This medication improves blood, bone, liver, and spleen problems caused by Gaucher disease. Taliglucerase does not correct the genetic problem, and treatment must be continued for life.

How to Use This Medication

This medication is given slowly, usually over 1 to 2 hours, into a vein as directed by your doctor, usually every 2 weeks. The dosage is based on your weight, medical condition, and response to treatment.

If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Do not shake while mixing the solution. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Discard any unused prepared medication. Do not save for later use. Learn how to store and discard medical supplies safely.

Taliglucerase may rarely cause side effects (such as headache, chest pain, nausea/vomiting, dizziness, increased blood pressure, weakness/tiredness, back/joint pain, flushing, coughing) while it is being given and for a short time after the infusion has stopped. Your doctor may decide to temporarily stop or slow down the medication infusion if this happens during your treatment. Tell your healthcare professional right away if you have any of these symptoms. Your doctor may direct you to take other medications (such as antihistamines, drugs for fever, or corticosteroids such as prednisone) to treat your reaction and before your next treatment(s) to prevent these reactions from happening again.

Tell your doctor if your condition persists or worsens. Blood, liver, and spleen problems usually improve in the first year of treatment. It may take 2 to 3 years of treatment to see the full benefit to your bones.

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Information expires December 2020.