epclusa Food, Alcohol, Supplements and Drug Interactions

EPCLUSA

QTY 28 • 400-100 MG • Tablet • Near 77381

SOFOSBUVIR; VELPATASVIR (soe FOS bue veer; vel PAT us veer) treats infections caused by the hepatitis C virus. It is a combination of two antiviral medications. It will not treat colds, the flu, or infections caused by bacteria.

EPCLUSA Lifestyle Interactions

Sofosbuvir 400mg, Velpatasvir 100mg, Oral tablet

Grapefruit juice

· Severity: Moderate

· Notes for Consumers: Although an interaction is possible, these drugs can be used together with caution. It is possible that side effects, such as a reduced number of red blood cells, may develop if these drugs are given together. Symptoms may include being tired or weak, dizziness, or cold hands or feet. If you notice any new or worsening side effects, contact your prescriber immediately.

· Notes for Professionals: Taking velpatasvir with grapefruit juice may increase the plasma concentrations of velpatasvir, potentially resulting in adverse events. Velpatasvir is a substrate of the drug transporter P-glycoprotein (P-gp); grapefruit is an inhibitor of P-gp. Grapefruit is also an inhibitor of the hepatic enzyme CYP3A4. Velpatasvir is a CYP3A4 substrate.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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Prescription prices may vary from pharmacy to pharmacy and are subject to change. The pricing estimates given are based on the most recent information available and may change based on when you actually fill your prescription at the pharmacy.

DISCOUNT ONLY - NOT INSURANCE. Discounts are available exclusively through participating pharmacies. The range of the discounts will vary depending on the type of prescription and the pharmacy chosen. This program does not make payments directly to pharmacies. Members are required to pay for all prescription purchases. Cannot be used in conjunction with insurance. You may contact customer care anytime with questions or concerns, to cancel your registration, or to obtain further information. This program is administered by Medical Security Card Company, LLC, Tucson, AZ.

*Average and up to savings percentages are based on all discounted prescriptions that were run through the WellRx program in 2022. Discount percentages represent savings provided off of pharmacies’ retail prices for consumers who do not have a discount program and pay cash.

The day supply is based upon the average dispensing patterns for the specific drug and strength. The Program, as well as the prices and the list of covered drugs, can be modified at any time without notice.

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