ATORVASTATIN CALCIUM
  • ATORVASTATIN CALCIUM

  • (Generic for LIPITOR)
  • QTY 30 • 40 MG • Tablet • Near 77381

ATORVASTATIN (a TORE va sta tin) is known as a HMG-CoA reductase inhibitor or 'statin'. It lowers the level of cholesterol and triglycerides in the blood. This drug may also reduce the risk of heart attack, stroke, or other health problems in patients with risk factors for heart disease. Diet and lifestyle changes are often used with this drug.

ATORVASTATIN CALCIUM Lifestyle Interactions

Atorvastatin Calcium 40mg, Oral tablet

Grapefruit juice

· Severity: Major

· Notes for Consumers: Side effects from Atorvastatin may get worse if you drink grapefruit juice. Do not take Atorvastatin with grapefruit juice. Discuss with your health care provider why Atorvastatin and grapefruit juice should not be taken together. Orange juice is safe to drink with Atorvastatin. Contact your prescriber immediately if you experience unexplained muscle aches, muscle pain or tenderness, general weakness or fatigue, side or back pain, or decreased urination while taking Atorvastatin.

· Notes for Professionals: Grapefruit juice should be avoided in patients taking atorvastatin to avoid the potential for drug accumulation and toxicity (i.e., myopathy and rhabdomyolysis). Grapefruit juice contains a compound that inhibits the CYP3A4 isozyme in the gut wall. In one pharmacokinetic study, coadministration of 240 ml grapefruit juice once daily with a single 40 mg dose of atorvastatin resulted in a 37% increase in the AUC and a 16% increase in Cmax of atorvastatin. Excessive consumption of grapefruit juice (i.e., >= 750 ml to 1.2 L/day) has been reported to result in an up to 2.5-fold increase in AUC and/or a 71% increase in Cmax of atorvastatin.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

DISCLAIMER: This content is provided for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.

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