BUDESONIDE (Generic for PULMICORT)

Budesonide 0.5mg/2mL, Nebulizer suspension

Grapefruit juice

· Severity: Major

· Notes for Consumers: Grapefruit juice can increase the amount of oral Budesonide (Entocort-EC) that your body absorbs. Grapefruit juice and grapefruit-containing foods may increase the side effects of oral Budesonide. If possible, you should avoid grapefruit or grapefruit juice while taking Entocort-EC. At the very least, avoid large changes (i.e., either increases or decreases) in your daily intake of grapefruit and grapefruit juice. Grapefruit juice is not expected to interact significantly with inhaled or nasal Budesonide (Pulmicort or Rhinocort).

· Notes for Professionals: Grapefruit juice, an inhibitor of gut mucosal CYP3A4, roughly doubles the bioavailability of oral budesonide. Patients should not eat grapefruit or drink grapefruit juice during the entire treatment period with oral budesonide.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>