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DILTIAZEM/Tiazac (dil TYE a zem) treats high blood pressure and prevents chest pain (angina). It works by relaxing the blood vessels, which helps decrease the amount of work your heart has to do. It belongs to a group of medications called calcium channel blockers.
Diltiazem Hydrochloride 360mg, Oral capsule, extended release pellets 24 hour
Alcohol
· Severity: Major
· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication increases the risk for dangerously low blood pressure. Contact your care team right away if you experience dizziness, feeling faint or lightheaded, or blurry vision.
· Notes for Professionals: Advise patients to avoid alcohol consumption while taking diltiazem; there may be additive effects on blood pressure that may increase the risk for orthostatic hypotension, dizziness or syncope. Alcohol also increases the rate at which some controlled and extended-release formulas of diltiazem (such as Cardizem CD) release diltiazem in vitro. This effect may lead to more rapid absorption and an increase in the systemic exposure of diltiazem, and associated dose-related adverse reactions.
Diltiazem Hydrochloride 360mg, Oral capsule, extended release pellets 24 hour
Grapefruit juice
· Severity: Moderate
· Notes for Consumers: Although less likely than with some other Calcium-Channel Blockers, Grapefruit juice and grapefruit-containing foods may increase the side effects of Calcium-Channel Blockers. Do not significantly increase grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible. If your heart rate or blood pressure drops too low while taking this medicine, you may become dizzy or feel faint; do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away while taking this medicine. If you notice new or increased swelling of your legs or ankles, tell your health care provider.
· Notes for Professionals: Current data suggest that grapefruit juice has a limited effect on diltiazem bioavailability. The mechanism is most likely due to inhibition of CYP3A4 isoenzymes in the gut by inhibitory compounds within grapefruit juice, resulting in reduced first-pass drug metabolism. It is generally recommended to avoid grapefruit juice during calcium-channel blocker therapy.
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Number of Uses:
taztia xt
360 MG | CAP SA 24H | 90 units
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